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Ashley Leak Bryant, PhD, RN-BC, OCN

Associate Professor and Anne Belcher Interprofessional Faculty Scholar in Nursing

ashley_bryant@unc.edu

919.966.5329

The University of North Carolina at Chapel Hill
School of Nursing
Carrington Hall, CB #7460
Chapel Hill, NC 27599-7460

Office: 401

Currently Accepting PhD Students

Dr. Ashley Leak Bryant, Associate Professor at the University of North Carolina at Chapel Hill School of Nursing and Anne Belcher Interprofessional Faculty Scholar in Nursing, is a clinical and research expert in care of adults with blood cancers during and beyond treatment. These blood cancers include lymphomas, leukemias, and multiple myeloma, which, although occurring across the life span, are diagnosed most often in older adults. Her research concentrates in these 2 areas: 1) developing and testing palliative and supportive care interventions for older adults with acute leukemia and 2) exploring the use of patient reported symptoms and quality of life in adults with blood cancers. She is certified in both gerontological (RN-BC) and oncology (OCN) nursing. She is also actively involved with UNC Project-Malawi, Kamuzu Central Hospital, and Kamuzu College of Nursing to build the oncology nursing workforce.

Dr. Bryant earned her BSN and MSN-Nursing Administration from UNC-Greensboro, PhD in Nursing from UNC-Chapel Hill, and completed post-doctoral training in cancer care quality at the Gillings School of Global Health at UNC-Chapel Hill.

2019–present Anne Belcher Interprofessional Faculty Scholar in Nursing

2019 Faculty Award for Excellence in Doctoral Mentorship and Education, UNC School of Nursing

2017-2019 NIH Loan Repayment Program Clinical Scholar

2017 ONS Victoria Mock New Investigator Award

2016 ONS Excellence in Care of the Older Adult with Cancer

2014 Lawrence S. Bloomberg Faculty of Nursing, University of Toronto Emerging Nurse Scholar

2011-2014 American Nurses Credentialing Center (ANCC), Gerontology Content Expert Panel Member

2010 Gordon H. DeFriese Career Development in Aging Research Award, Institute of Aging, The University of North Carolina at Chapel Hill

2010 The Pauline W. Brown Diversity Scholarship Award, The University of North Carolina at Chapel Hill School of Nursing

2009-2011 Nurse Educators for Tomorrow, College Foundation for North Carolina

2009 Interdisciplinary Best Poster, Interdisciplinary Center for Aging Research: Uniting Scientists (ICARUS) Award, NC Aging Exchange

REFEREED PAPERS

Acute Leukemia

Bryant, A.L., Chan, Y., Richardson, J., Foster, M., Owenby, S., & Wujcik, D. (2020). Understanding Barriers to Oral Therapy Adherence in Adults with Acute Myeloid Leukemia. Journal of Advanced Practitioner in Oncology, 11(4), 342-350. doi.org/10.6004/jadpro.2020.11.4.2

Bryant, A.L., Leblanc, T., Albrecht, T., Chan, Y., Richardson, J., Foster, M., Dang, M., Dudley, W., & Owenby, S., & Wujcik, D. (2020). Oral adherence in adults with acute myeloid leukemia (AML): Results of a mixed methods study. Supportive Care in Cancer. DOI: 10.1007/s00520-020-05349-5

Bryant, A.L., Tan, X., Coffman, E., Phillips, B., Tan, X., Bullard, E., Hirschey, R., Bradley, J., Bennett, A., Stover, A., Song, L., Shea, T., Wood, W.A. (2020). Pilot Randomized Trial of an Electronic Symptom Monitoring and Reporting Intervention for Hospitalized Adults Undergoing Hematopoietic Stem Cell Transplantation. Supportive Care in Cancer, doi: 10.1007/s00520-019-04932-9. PMID: 31222392.

Albrecht, T. & Bryant, A.L. (2019). Psychological and Financial Distress Management in Adults with Acute Leukemia. Seminars in Oncology Nursing.

Bryant, A.L & LeBlanc, T. (2019). Introduction to Acute Leukemia. Seminars in Oncology Nursing.

Bryant, A.L., Drier, S.W., Lee, S. & Bennett, A.V. (2018). A systematic review of patient reported outcomes in phase II or III clinical trials of myelodysplastic syndromes and acute myeloid leukemia. Leukemia Research, 7:70, 106-116. PMID: 29925044

Coffman, E.M., Bryant, A.L., Deal, A.M., Wang, Y., Hanson, E.D., Phillips, B., Bailey, C., Foster, M., Wood, W. A., Muss, H., & Battaglini, C. L. (2018). Feasibility and Safety of Cardiopulmonary Exercise Testing in Acute Leukemia Patients during Induction Chemotherapy. Annals of Hematology & Oncology, 5(1): 1188.

Leak Bryant A., Gosselin, T., Coffman, E.M., Phillips, B., Gray, T.F., Knafl, G.J., Klepin, H.D., Wood, W.A., Muss, H., & Reeve, B.B. (2018). Symptoms, Mobility and Function, and Quality of Life in Adults with Acute Leukemia During Initial Hospitalization. Oncology Nursing Forum. 1;45(5):653-664. doi: 10.1188/18.ONF.653-664. PMID:  30118443

Bryant, A.L., Coffman, E., Bullard, E., Hirschey, R., Bradley, J., Stover, A., Wood, W. A., & Bennett, A.V. (2018). Experiences of Inpatient Bone Marrow Transplant Nurses and Providers using Electronic Symptom Reporting. Journal of Oncology Practice, 14(8), e496-e504. PMID: 29944435.

Bryant, A.L., Walton, A.M., Phillips, B., Bailey, C., Pergolotti, M., Mayer, D.K., Battaglini, C. (2017). Perceived Benefits and Barriers to Exercise for Recently Treated Adults with Acute Leukemia. Oncology Nursing Forum, 44(4), 413-420, doi: 10.1188/17.

Bryant, A.L., Deal, A.M., Battaglini, C., Phillips, B., Bailey, C., Pergolotti, M., Coffman, E., Hackney, A.C., Wood, W.A., Mayer, D.K., Muss, H., Reeve, B.B. (2017). The Effects of Exercise on Patient Reported Anxiety, Depression, Fatigue, Sleep Disturbances, and Quality of Life in Newly Diagnosed Adults with Acute Leukemia during Induction Treatment: Exercise and Quality of Life in Leukemia Patients (EQUAL) Trial. Integrative Cancer Therapies, doi: 10.1177/1534735417699881.

Story, C., Bryant, A.L., Phillips, B., Bailey, C. Shields, E., & Battaglini, B. (2016). Comparison Methods for Determining Aerobic Exercise Intensity using Heart Rate in Acute Leukemia Patients prior to Induction Chemotherapy. Biological Research for Nursing, 18(4), 432-438.

Bryant, A.L., Walton, A.M., Shaw-Kokot, J., Mayer, D., & Reeve, B.B. (2015). Symptoms and Quality of Life in Adult Survivors of Acute Leukemia: A Systematic Review. Oncology Nursing Forum, 42(2), E91-E101.

Bryant, A.L., Deal, A., Walton, A., Wood, W., Muss, H., & Mayer, D. (2015). Use of ED and hospital services for patients with acute leukemia after induction therapy: One Year Following Diagnosis. Leukemia Research, 39(4),406-410.

Albrecht, T., A., Walton, A.M., Bryant, A.L. (2015). The Unique Supportive Care Needs of a Mother with Acute Myeloid Leukemia during Treatment. Clinical Journal of Oncology Nursing, 19(1), 16-19.

Bryant, A.L., Walton, A.M., & Albrecht, T.A. (2014). Management of febrile neutropenia in a patient with acute leukemia. Journal of Emergency Nursing, 40, 377-381.

Creedle, C., Leak, A., Deal, A., Walton, A., Talbert, G., Riff, B., & Hornback, A. (2012). The Impact of a CarePartner Program on Two Inpatient Oncology Units. Journal of Cancer Education, 27, 250-256.

Lymphoma

Noonan, D., Leblanc, M., Mayer, D.K., Bryant, A.L., Zimmerman, S., Smith, S.K. (2020). Quality of Life and Impact of Cancer: Differences in Rural and Non-Rural Non-Hodgkin Lymphoma Survivors. Journal of Rural Health. doi: 10.1111/jrh.12420.

Bryant, A.L., Smith, S., Zimmer, C., Crandell, J., Jenerette, C., Bailey, D., Zimmerman, S., & Mayer, D.K. (2015). An exploratory path model of the relationships between positive and negative adaptation to cancer on quality of life among non-Hodgkin lymphoma survivors. Journal of Psychosocial Oncology.

Leak, A., Smith, S., Crandell, J., Jenerette, C., Bailey, D., Zimmerman, S., & Mayer, D. (2013). Demographic and disease characteristics associated with non-Hodgkin Lymphoma Survivors’ quality of life. Oncology Nursing Forum, 40, 157-162.

Leak, A., Mayer, D., & Smith S. (2011). Quality of life among non-Hodgkin’s lymphoma survivors: An integrative literature review. Leukemia and Lymphoma, 52, 972-985.

Multiple Myeloma

*Leblanc, M., LeBlanc, T., Bryant, A.L., Hirschey, R., & Smith, S. (2019). How are patient-reported outcomes and symptoms being measured in adults with relapsed/refractory multiple myeloma? A Systematic Review. Quality of Life Research. DOI: 10.1007/s11136-019-02392-6

Gero-Oncology, Physical Activity, Quality of Life Papers

Hirschey, R., Bryant, A.L., Macek, C., Battaglini, C., Santacroce, S., Courneya, K., Sheeran, P. (2020). Psychosocial Constructs that Predict Physical Activity in Cancer Survivors: A Meta-analysis. Health Psychology. DOI: 10.1037/hea0000845

Jung, A., Nielsen, M.E., Crandell, J.L., Palmer, M.H., Bryant, A.L., Smith, S.K., & Mayer, DK. (2019). Quality of Life in Non-Muscle-Invasive Bladder Cancer Survivors: A Systematic Review. 42,(3):E21-E33. doi: 10.1097/NCC.0000000000000606.

Jung, A., Nielsen, M.E., Crandell, J.L., Palmer, M.H., Smith, S.K., Bryant, A.L., & Mayer, D.K. (2020). Health-related quality of life among non-muscle-invasive bladder cancer survivors: a population-based study. BJU International, 125(1):38-48. doi: 10.1111/bju.14888.

Von, Ah, D., Brown, C.G., Brown, S.J., Bryant, A.L., Davies, M., Dodd, M., Ferrell, B., Hammer, M., Knobf, M.T., Knoop, T.J., LoBiondo-Wood, G., Mayer, D.K., Miaskowski, C., Mitchell, S.A., Song, L., Watkins, Bruner, D., Wesmiller, S., & Cooley, M.E. (2019). Research Agenda of the Oncology Nursing Society: 2019-2022. Oncology Nursing Forum, 46(6),654-669. doi: 10.1188/19.ONF.654-669. PMID: 31626621

Pergolotti, M., Deal, A., Williams, G., Bryant, A.L., McCarthy, L., Nyrop, K., Reeve, B. B., Basch, E., & Muss, H. (2019). Older Adults with Cancer: A Randomized Control Trial of Occupational and Physical Therapy. Journal of American Geriatrics Society, https://doi.org/10.1111/jgs.15930

Pergolotti, M., Deal, A.M., Bryant, A.L., Bennett, A. V., Severino, E., Covington, K., Lucas, K., & Williams, G. R. (2019). Senior Sway: Using a mobile application to measure fall risk. Journal of Geriatric Physical Therapy, doi: 10.1519/JPT.0000000000000223 

Newman, R., Alfano, C., Radomski, M.V., Pergolotti, M., Wolf, T., Speight, A., Bryant, A.L., Voelbel, G., de Moor, J., Nitkin, R., Daniels, E., Braveman, B., Walker, R.K., Williams, G., Winters-Stone, K.M., Cheville, A., Campbell, S., Lawlor, M., King, A., Ness, K., Drivastava, P., Lyons, K. (2019). Catalyzing Research to Optimize Cancer Survivors’ Participation in Work and Life Roles. Occupation, Participation, and Health, doi: 10.1177/1539449219844749.

Pergolotti, M., Deal, A., Williams, G.R., Bensen, J., Bryant, A.L., Muss, H., Reeve, B.B. (2017). Activities, Function, and Health-Related Quality of Life (HRQOL) of Older Adults with Cancer. Journal of Geriatric Oncology, 8(4), 249-254.

Burhenn, P., Bryant, A.L., & Mustian, K. (2016). Exercise Promotion in Geriatric Oncology. Current Reports in Oncology, 18(9):58-64.

Mariano, C., Alston, S., West, J., Deal, A., Williams, G., Dixon, S., Bryant, A.L., Jolly, T., & Muss, H. (2015). Geriatric assessment in older adults during unplanned hospitalizations: an opportunity in disguise. The Oncologist, 20(7),767-772.

Leak, A., Mayer, D., Wyss, A., Travers, D., & Waller, A. (2013). Why do cancer patients die in the emergency department? An analysis of NC 2008 ED visits. American Journal of Hospice and Palliative Medicine, 30,178-182.

Mayer, D., Travers, D., Wyss, A., Leak, A., & Waller, A.  (2011). Why do cancer patients visit emergency departments? Results of a 2008 population study in North Carolina. Journal of Clinical Oncology, (29), 2686-2688.

Global Health

Bingo, S. (2020). What is the role of the oncology nurse leader in building oncology nursing capacity in Malawi? Clinical Journal of Oncology Nursing, 24(2), 215. (mentored nurse leader)

Anarp, S. (2019). How Does a Swedish Nursing Student View Clinical Oncology Care in the United States? Clinical Journal of Oncology Nursing, 23(2), 224. (mentored undergraduate student)

Ivanov, L. & Hu, J., & Leak, A. (2010). Immigrant women’s cancer screening behaviors. Journal of Community Health Nursing, 27, 32-45. PMID: 20131135

Smith-Miller, C., Leak, A., Harlan, C., Dieckmann, J., & Sherwood, G. (2010). Leaving the comfort of the familiar”: Fostering workplace cultural awareness through short-term global experiences. Nursing Forum, 45, 18-28. PMID: 20137021

Leak, A., Ivanov, L., & Brown, H. (2006). Nursing administration in Russia. The Journal of Nursing Administration, 36, 177-180. PMID: 16609339 

FUNDED (ACTIVE)

Role Title Total Direct Amount (FTE if available) Percent Effort Agency Dates
Co-Investigator Meeting Educational Needs Through Optimization of Retention Strategies for Students (MENTORS2) 1,900,000 10% HRSA 2017-2021
Junior Faculty Advisory Committee NCCU/LCCC Disparities Partnership (U54) – Administrative Core $137,391 3% National Cancer Institute (2U54CA156733-06) 2015-2020

 

FUNDED (COMPLETED)

Role Title Total Direct Amount (FTE if available) Percent Effort Agency Dates
K Scholar Longitudinal Assessment of Symptoms, Functional Status, and Quality of Life in Adults with Acute Leukemia $209,908

 

75% National Cancer Institute, UNC Oncology Translational Award (5K12CA120780-07) (K12 Paul Calabresi Career Development Award in Clinical Oncology) 2014-2017
Co-I Implementation of Patient-Reported Outcomes Endpoints in the Acute Myeloid Leukemia Phase IB $20,000 5% Leukemia and Lymphoma Society

 

2015-2016
PI Exploring barriers and benefits of an inpatient exercise intervention in newly diagnosed patients with acute leukemia $5,000 0% The University of North Carolina at Chapel Hill, School of Nursing Support Pilots for Advancing Research and Knowledge (SPARK)

 

2014-2015
PI The Effects of Exercise on Patient-Reported Outcomes in Newly Diagnosed Adults with Acute Leukemia during Induction Treatment: Exercise and Quality of Life in Leukemia Patients (EQUAL) $25,000 0% Alvin R. Tarlov and John E. Ware Post-Doctoral Research Award in Patient Reported Outcomes 2012-2015
Post-Doctoral Fellow Cancer Care Quality Training Post-Doctoral Fellowship $240,000 100% National Cancer Institute (R25CA116339) 2011-2013
Co-I Measuring the Impact of an Oncology Care Partner Program on Caregiver Burden. $40,000 10% University Cancer Research Fund (UL1RR025747) 2009-2011
PI Quality of life of older non-Hodgkin lymphoma survivors. $200,00 100% John A. Hartford Foundation

 

2009-2011
Pre-Doctoral Fellow Institutional NRSA Grant, Interventions to Prevent and Manage Chronic Illness. $100,000 100% National Institute of Nursing Research (5T32NR007091) 2007-2009

Palliative and supportive care interventions

Patient reported symptoms and outcomes

Quality of life in blood cancers