Placental DNA Methylation, Maternal Hardship and Child Neurodevelopmental Outcomes

Placental DNA Methylation, Maternal Hardship and Child Neurodevelopmental Outcomes

Principal InvestigatorHudson Santos, PhD, RN
Funded by: National Institute for Nursing Research | K23 Grant

Children born extremely preterm may experience impairment of the growth and development of their brain and central nervous system. DNA methylation is a biological process that can change the activity of a DNA segment, and this study will determine how that process relates to maternal hardship and neurodevelopmental impairment in extremely preterm children with an ultimate goal toward preventing or minimizing that impairment. By providing the groundwork to inform future interventions, this research could lead to improved quality of life for the 16,500 families with a child surviving extremely premature birth annually in the US.

Principal Investigator