Lorinda A. Coombs, PhD, MSN, FNP-BC, AOCNP, FAAN
Associate Professor (Tenure Track)
School of Nursing
Campus Box #7460
Chapel Hill, NC 27599-7460
Associate Professor (Tenure Track)
Dr. Lorinda A. Coombs is a clinician scientist and practicing oncology nurse practitioner whose research brings patients’ values into treatment decisions for older adults with advanced cancer. She is an Associate Professor at the UNC Chapel Hill School of Nursing and a member of the UNC Lineberger Comprehensive Cancer Center. She also continues clinical practice as an advanced practice provider in medical oncology at the N.C. Basnight Cancer Hospital.
Dr. Coombs leads the development of the Values Assessment Tool (VAsT). She co-created VAsT with patients, care partners, clinicians, and a community advisory board to help oncology teams understand what matters most to patients when making treatment decisions. Supported by the UNC Lineberger Comprehensive Cancer Center, her pilot work with women with metastatic breast cancer showed that VAsT was feasible and valued by patients. She is now extending this work to older adults with metastatic lung cancer as well as expanding it into international contexts within Korea. Her broader research uses mixed methods, cancer registry and claims data, and machine learning to study treatment decision-making, timely cancer diagnosis in underserved North Carolina communities, and the advanced practice workforce in cancer care. She has published more than 50 peer-reviewed articles in journals including the Journal of Clinical Oncology, Cancer, npj Digital Medicine, and Psycho-Oncology.
Before joining UNC in 2020, Dr. Coombs practiced for more than 15 years as a hematology/oncology nurse practitioner in California and Utah, including at San Francisco General Hospital, Stanford Cancer Center, and Kaiser Permanente. She earned her PhD in Nursing and Health Policy from the University of California, San Francisco, and completed an NIH T32 postdoctoral fellowship in cancer, caregiving, and end-of-life care at the University of Utah.
She was inducted as a Fellow of the American Academy of Nursing in 2025 and received the Oncology Nursing Certification Corporation’s Advanced Oncology Certified Nurse of the Year Award the same year. She serves on the Board of Directors of the Advanced Practitioner Society for Hematology and Oncology and as an Associate Editor of Policy, Politics & Nursing Practice. At UNC, she teaches across the MSN, DNP, and PhD programs, serves as faculty on a T32 training grant, and mentors nursing, pharmacy, and medical students in oncology and palliative care research.
Research interests: shared decision-making · patient values and goals of care · geriatric oncology · palliative care · timely cancer diagnosis · advanced practice workforce
Education:
PhD, University of California, San Francisco
Post-Master’s FNP, University of California, Los Angeles
MSN, San Francisco State University
BA, University of Michigan
2025 Fellow, American Academy of Nursing, Washington, DC
2025 Advanced Oncology Certified Nurse of the Year Award, Oncology Nursing Certification Corporation (ONCC), Oncology Nursing Society Annual Congress
2024 Competitively Selected Participant for the 2024 Advanced Workshop on Research Skills in Oncology, NCI Awardee Skills Development Consortium, Dana-Farber Cancer Institute
2023 Arti Hurria Manuscript of the Year Award, Journal of Geriatric Oncology, ‘Treatment decision conversations, symptoms, and functional status in older adults with advanced cancer: An exploratory study utilizing mixed methods’
2022 Chair, Nurse, and Home Care Workforce Shortage Session —Projections, Shortage, and Implications in COVID-19, AcademyHealth, Annual Research Meeting
Books and Chapters
1. Bryant, A.L., Coombs, L., Mayo, S., Malakian, A., & Albrecht, T. (2025). Palliative Care for Individuals Living with Hematological Malignancy. In Albrecht, T., Battista, V., Brody, A.A.& Coats, Editor (Eds.), Oxford Textbook of Palliative Nursing. Chapter 51. Oxford University Press, Oxford, England.
Refereed Papers/Articles
1. Crowder R, Crowder R, Fariman S, Joglekar N, Anderson D, Miller J, Walker S, Ray E, Ford-Pierce S, Reeve B, Bennett A, Mazor M, Deal A, Coombs LA. “Insight into who you are as a human being”: Perceptions of the Utility and Usability of a Values Assessment Tool (VAsT) for Women with Metastatic Breast Cancer. Cancer Control 2026;33. doi:10.1177/10732748261466394.
2. Crowder V, Cho Y, Teng CH, Anderson D, Batchelor M, Beeber A, Coombs LA, Richardson D, Sawyer A, Fogle R, Holliday A, Schwartz T, Leak Bryant A. “An opportunity to spend time with each other”: The Importance of Mealtimes for Carepartners of Older Adults with Acute Myeloid Leukemia and Myelodysplastic Syndromes. Journal of Geriatric Oncology, July 2026, Volume 17 (6), 10.1016/j.jgo.2026.102976.
3. Short A, Kuroki M, Leak Bryant A, Allman K, Fowler Gray T, Coombs LA. Utilizing a Palliative Care Needs Assessment for Adult Allogeneic Hematopoietic Stem Cell Transplants. Clinical Journal of Oncology Nursing, June 2026, Volume 30 (3) E49-E56 doi: 10.1188/26.CJON.E49-E56.
4. Laidley J, Lindvall C, Coombs LA, Tulsky J, Gray T. Patterns of Goals of Care Documentation in the Outpatient Oncology Setting: A Retrospective Cohort Study of Older Adults with Advanced Cancer. Journal of Palliative Medicine, April 2026 doi:10.1177/10966218261446776.
5. Gigas E, Zou B, Coombs LA, Schmidt P, Wilmoth MC, Khairat S. Factors associated with mortality in Appalachian nursing homes during the COVID-19 pandemic. The Permanente Journal 2026 doi.org/10.7812/TPP/25.220.
6. Coombs LA, Zhou X, Baggett C, Reeder-Hayes K, Diaz F, Weiss J, Thompson C, Lund JL. Exploring clinical pathways to a metastatic lung cancer diagnosis with latent class analysis. Cancer Epidemiology, Biomarkers, & Prevention 2026 doi.org/10.1158/1055-9965.EPI-25-1859.
7. Coombs LA, Leak Bryant A. Integrating Compassion Early: Palliative Care’s Role in Improving the Quality of Life and Psychological Well-Being for Individuals Undergoing Hematopoietic Stem Cell Transplantation. (Invited Commentary) Annals of Palliative Medicine, 2026 Jan; 15(1):15. doi:10.21037/apm-2025-aw-125.
8. Waters AR, Charlton B, Murray CR, Jones SR, Warner EL, Coombs LA, Donovan H, Deng Z, Ren D, Fredrickson B, Nichols H, Kent EE, Wheeler SB, Rosenstein DL, Tan KR. Association of Multi-Level LGBTQ+ Stigma and Hypervigilance with Health Outcomes Among LGBTQ+ Cancer Caregivers. Psycho-Oncology, 2026 doi:10.1002/pon.70379.
9. Baldwin EJ, Short A, Wehner K, Zanter A, Coombs LA. Improving Access to Advance Care Planning: Integrating Nurse-Driven Advance Care Planning Follow-Up for Adult Allogeneic Bone Marrow Transplant Patients. Journal of Hospice and Palliative Nursing. Dec 5, 2025; PMID: 41364092 doi:10.1097/njh.0000000000001193.
10. Fariman S, Ahmadi A, Trogdon J, Coombs LA, Elston Lafata J (shared senior authorship. Association of Patient-Provider Race/Ethnicity Concordance and Patient-Reported Shared Decision Making Among US Adults: A National Study, 2015–2021. Journal of General Internal Medicine 2025; PMID: 41402671 https://doi.org/10.1007/s11606-025-10052-4.
11. Coombs LA, Kim M. Efficacy of Web-Based Interventions in Psychological Distress Among Patients with Cancer: A Systematic Review and Meta-Analysis. Psycho-Oncology, 2025 Nov; 34(11):e70321; PMID: 41171029 Doi:10.1002/pon.70321.
12. Tomczik K, Niznik J, Coombs LA. “Who’s gonna take care of my babies?” The impact of children on treatment decisions for women with metastatic breast cancer: a qualitative analysis. BioMed Central Cancer, 2025, 1662 2025; PMID: 41152766 doi.org/10.1186/s12885-025-14953-9.
13. Kim M, Coombs LA. Effectiveness of web-based interventions on depression and anxiety in older adults: A systematic review and meta-analysis of randomized controlled trials. Archives of Geriatrics and Gerontology, 2025;139:106025; PMID: 40961807 doi: 10.1016/j.archger.2025.106025.
14. Waters AR, Kent EE, Murray CR, Jones SR, Warner EL, Coombs LA, Donovan H, Nichols HB, Wheeler SB, Rosenstein DL, Roberson ML, Tan KR. “How am I going to live? How am I going to pay rent?”: A Mixed Methods Investigation of Employment, Stigma, and Financial Hardship among LGBTQ+ Cancer Caregivers. Cancer Control, 2025;32; PMID: 40516028 doi: 10.1177/10732748251351105.
15. Coombs LA, Crowder V, Tan K, Ray EM, Ferrari RM, Kent EE, Reuland DS, Leak Bryant A, Black M. Co-creating and Refining a Values Assessment Tool (VAsT) for Women with Metastatic Breast Cancer. Psycho-Oncology, 2025; 34 e70173; PMID: 40344355 https://doi.org/10.1002/pon.70173.
16. Kim M, Tan K, Coombs LA. Effects of web-based interventions on cancer caregivers’ burden and quality of life: A systematic review and meta-analysis. Palliative and Supportive Care, 2025;23: e134; PMID: 40676719 doi:10.1017/S1478951525100370.
17. Crowder, V., Bankole, A.O., Conklin, J.L., Sawyer, A.S., Holliday, A.M., Fogle, R., Coombs, L., Richardson, D., Beeber, A.S., Batchelor, M., Schwartz, T., & Bryant, A.L. Nutrition and acute myeloid leukemia and myelodysplastic syndromes in older adults (≥60): A scoping review. Journal of the Academy of Nutrition and Dietetics, 2025; PMID: 40544958 https://doi:10.1016/j.jand.2025.06.028.
18. Causey L, Leak Bryant A, Smith B, Coombs LA. Improving Survivorship Care Plan Delivery with Social Determinants of Health Screening and Nurse Navigation. Clinical Journal of Oncology Nursing, 2025; 29(2): E60-E69; PMID: 40096557 doi: 10.1188/25.CJON.E60-E69.
19. Short A, Kuroki M, Coombs LA. Palliative Care Referral in Adult Allogeneic Hematopoietic Stem Cell Transplants: An Integrative Literature Review American Journal of Hospice and Palliative Medicine, 2025 Sep; 42(9): 962-970, PMID: 39324492 doi.org/10.1177/1049909124128740.
20. Kuroki M, Short A, Coombs LA. Chlorhexidine Gluconate Treatment Adherence Among Nurses and Patients to Reduce Central Line-associated Bloodstream Infections: A Literature Review. Clinical Journal of Oncology Nursing, 2025;29(2): E37-E46; PMID: 40096554 doi.org/10.1188/25.CJON.E37-E46.
21. Gigas E, O’Neel N, Coombs LA, Conklin J, Wilmoth M, Zou B, Schmidt P, Khairat S. Place-Based Disparities Among Nursing Homes During the COVID-19 Pandemic: A Systematic Literature Review. Health Equity, 2025 Jan 22;9(1):73-86. PMID: 40123846 doi:10.1089/heq.2024.0091.
22. Stover A, Liang D, Mueller D, Kurtzman R, Ikemeh C, Center C, Acharya S, Brese J, Buhlinger K, Chen K, Colmenares E, Faso A, Muluneh B, Patel B, Reichard J, Shah RM Tilkens M, Valgus J, Coombs LA, Elston Lafata J, Lund J, Ray E, Mody G, Haston Vest M. Pharmacist-facilitated Patient Reported Outcome Measure (PROM) monitoring: Developing an EHR SmartForm to monitor side effects of oral oncolytics during telehealth encounters. Quality of Life Research,2025 Jan; 34(1):201-217. PMID: 39404983 doi.org/10.1007/s11136-024-93789-8.
23. Coombs LA & Hammer AJ. Build Bridges, Not Walls: A Call for Collaboration in Oncology With PhD and DNP Colleagues to Improve Research. Oncology Nursing Forum, 2024 Oct 17;51(6): 500-501. doi: 10.1188/24.ONF.500-501.
24. Coombs LA, Kim M. Effects of web-based interventions on quality of life among patients with breast cancer: A systematic review and meta-analysis of randomized controlled trials. Cancer Medicine, 2024 Sep; 13(18)e70230. PMID: 39359165 doi.org/10.1002/cam4.70230.
25. Keeney T, Miller A, Gilissen J, Coombs LA, Ritchie C, McCarthy E. Identification of older adults with Alzheimer’s and related dementia among patients newly diagnosed with cancer: A comparison of methodological approaches. Journal of Geriatric Oncology, 2024 Sep;15(7):101842. PMID: 39122573 doi.org/10.1016/j.jgo.2024.101842.
26. Mooney K, Beck S, Wilson C, Coombs L, Whisenant M, Moraitis AM, Sloss EA, Alekhina N, Lloyd J, Steinbach M, Nicholson B, Iacob E, Donaldson G. Assessing Patient Perspectives and the Health Equity of a Digital Cancer Symptom Remote Monitoring and Management System. JCO Clinical Care Informatics, 2024 Jul:8:e2300243. PMID: 39042843 doi.org/10.1200/CCI.23.0024.
27. Kim M, Tan K, Coombs LA. Efficacy of Web-Based Interventions on Depression and Anxiety in Cancer Caregivers: A Systematic Review and Meta-Analysis. Psycho-Oncology, 2024 Jul;33(7):e9301. PMID: 39039753 doi.org/10.1002/pon.930.
28. Mooney K, Coombs LA, Whisenant M, Moraitis AM, Steinbach M, Sloss E, Lloyd J, Alekhina N, Wilson C, Berry P, Kang Y, Iacob E, Donaldson G. Impact of an Automated, Remote Monitoring and Coaching Intervention in Reducing Cancer Family Caregiving Burden: A Multisite Randomized Controlled Trial. Cancer, 2024 Apr 1;130(7):1171-1182. PMID: 38009953 doi: 10.1002/cncr.35131.
29. Bryant AL, Morgan M, Coombs LA, Hirschey R, Betancur S, Xu J, Wehner K, Mayer D. Development of an Undergraduate Oncology Nursing Elective with a Focus on Palliative Care. Nurse Educator, 2024 May-Jun;49(3):E172-174. PMID: 37944158 doi.10.1097/NNE.0000000000001547.
30. O’Neil B, Dindinger-Hill K, Gill H, Coombs LA, Haaland B, Ying J, Nelson R, McPherson J, Kirchoff AC, Ulrich CM, Huber J, Beck A, Mooney K. Cost and Utilization Outcomes of Huntsman at Home, A Novel Oncology Hospital at Home Program. Journal of the Post-Acute and Long-Term Care Medical Association, 2024 Apr;25(4):610-613, PMID: 37541650 doi:10.1016/j.jamda.2023.06.030.
31. Durbin Weaver S, Singh S, Sharpe L, Reuland DS, Coombs LA. Values Assessment Tools in Advanced Cancer: A Comprehensive Clinical Literature Review, Clinical Journal of Oncology Nursing, 2023 Sep 15;27(5):525-531, PMID: 37729449 doi:10.1188/23.CJON.525-531.
32. Leung B, Pilleron S, Bastiaannet E, Coombs LA, Jin R, Kantilal K, Kantilal K, Kenis C, Kobekyaa F, Kosmari L, Krok-Schoen JL, Li J, Mac Eochagáin C, Newton L, Ruegg T, Stolz-Baskett P, Zhao Y, Bradley C, Puts M, Haase KR. Cancer-treatment related decision-making among culturally and linguistically diverse older adults with cancer: A scoping review by the International Society of Geriatric Oncology Nursing and Allied Health Interest Group. Journal of Geriatric Oncology, 2023 Nov;14(8):101607, PMID: 37633779 doi:10.1016/j.jgo.2023.101607.
33. Tan KR, Waters AR, Chen Q, Hendricks BA, Coombs LA, Kent E. Inequities among Cancer Caregivers with Diverse Identities: A Review of Literature and Future Directions. Current Oncology Reports, 2023 Jul;25(7):803-812, PMID: 37043117 doi:10.1007/s11912-023-01415-3.
34. Mooney K, Whisenant M, Wilson C, Coombs LA, Lloyd J, Alekhina N, Sloss E, Steinbach M, Moraitis AM, Berry P, Iacob E, Donaldson G. Technology-Assisted mHealth Caregiver Support to Manage Cancer Patient Symptoms: A Randomized Controlled Trial. Journal of Pain and Symptom Management, 2023 Jul;66(1):33-43. PMID: 36889453 doi: 10.1016/j.jpainsymman.2023.02.320.
35. Coombs LA, Neller S, Wilson C, Mihas P, Reuland D, Muss H, Mooney K. Older Adults with Advanced Cancer: Treatment Decision Conversations, Symptoms and Functional Status, An Exploratory Study Using Mixed Methods. Journal of Geriatric Oncology, 2023 Mar;14(2):101414, PMID: 36503882 doi:10.1016/j.jgo.2022.12.002.
36. Jensen CE, Heiling HM, Beke KE, Deal AM, Bryant AL, Coombs LA, Foster MC, Richardson DR. Time spent at home among older adults with acute myeloid leukemia receiving Azacitidine or Venetoclax-based regimens. Haematologica, 2023 Apr 1;108(4):1006-1014. PMID: 35861016 doi:10.3324/haematol.2022.280728.
37. Coombs LA, Orlando A, Wang W, Shaw P, Rich A, Lakhtakia S, Titchener K, Adamson B, Miksad R, Mooney K. A machine learning framework supporting prospective clinical decisions applied to risk prediction in oncology. Nature Portfolio Journal Digital Medicine, 2022 Aug 16;5(1):117. PMID: 35974092 doi: 10.1038/s41746-022-00660-3.
38. Sisler S, Kent-Marvick J, Wawrzynski SE, Pentecost R, Coombs LA. Social isolation and Social Media Consumption among Graduate students during COVID-19: An Examination using Social Comparison Theory. International Journal of Nursing Health Care Research (Lisle), 2021;4(9):1257, PMID: 35079736 doi:10.29011/2688-9501.101257.
39. Whisenant MS, Coombs LA, Wilson C, Mooney K. Symptom-related patient-provider communication among women with breast cancer receiving chemotherapy. European Journal of Oncology Nursing, 2021 Dec; 55:102064, PMID: 34800823 doi:10.1016/j.ejon.2021.102064.
40. Titchener K, Coombs LA, Dumas K, Beck A, Ward J, Mooney K. Huntsman at Home, an Oncology Hospital at Home Program. New England Journal of Medicine Catalyst Innovations in Healthcare Delivery. 2021 Oct 20; Vol 2;(11) doi:10.1056/CAT.21.0248.
41. Mooney K, Titchener K, Haaland B, Coombs LA, O’Neil B, Nelson R, McPherson J, Kirchoff AC, Beck AC, Ward JH. Evaluation of Oncology Hospital at Home: Unplanned Health Care Utilization and Costs in the Huntsman at Home Real-World Trial. Journal of Clinical Oncology, 2021 Aug 10;39(23):2586-2593, PMID: 33999660 doi:10.1200/JCO.20.03609.
42. Thomas Hebdon MC, Coombs LA, Reed P, Crane TE, Badger TA. Self-Efficacy in Caregivers of Adults Diagnosed with Cancer: An Integrative Review. European Journal of Oncology Nursing, 2021 Jun; 52:101933, PMID: 33799022 doi: 10.1016/j.ejon.2021.101933.
43. Coombs LA, Ellington L, Fagerlin A, Mooney K. Age is Not a Barrier: Older Adults with Cancer Derive Similar Benefit in a Randomized Controlled Trial of a Remote Symptom Monitoring Intervention Compared with Younger Adults. Cancer Control, 2020 Jan-Dec;27(1):1073274820968878, PMID: 33153313 doi:10.1177/1073274820968878.
44. Coombs LA, Noonan K, Diane Barber F, Mackey H, Peterson ME, Turner T, LeFebvre K. Oncology Nurse Practitioner Competencies: Defining Best Practice in the Oncology Setting. Clinical Journal of Oncology Nursing, 2020 Jun 1;24(3):296-304. PMID: 32441678, doi:10.1188/20.CJON.296-304.
45. Coombs LA. Chronic Neutrophilic Leukemia: A Case Report of a Rare Myeloproliferative Neoplasm with a CSF3R Mutation. Journal of Advanced Practitioners in Oncology, 2019 Nov-Dec;10(8):853-857, PMID: 33425468 doi:10.6004/jadpro.2019.10.8.6.
46. Rosenzweig MQ, Bailey DE, Bush NJ, Coombs LA, Lehto RH, Loerzel V, Sun V, Mooney K, Cooley ME. Mentorship for Oncology Nurse Scientists: Strategies for Growth from the Oncology Nursing Society Mentorship Task Force. Oncology Nursing Forum, 2019 Nov 1;46(6):769-774, PMID: 31626617 doi:10.1188/19.ONF.769-774.
47. Coombs LA, Max W, Kolevska T, Tonner C, Stephens C. Nurse Practitioners, and Physician Assistants: An Underestimated Workforce for Older Adults with Cancer. Journal of the American Geriatrics Society, 2019 Jul;67(7):1489-1494, PMID: 31059140; doi:10.1111/jgs.15931.
48. Coombs LA, Stephens C. Identifying the Contribution of Nurse Practitioners in the Care of Older Adults with Cancer. Oncology Nursing Forum, 2019 May 1;46(3):277-282, PMID: 31007255 doi:10.1188/19.ONF.277-282.
49. Hunt LJ, Coombs LA, Stephens CE. Emergency Department Use by Community-Dwelling Persons with Dementia in the United States: An Integrative Review. Journal of Gerontology Nursing, 2018 Mar 1;44(3):23-30, PMID: 29355877; doi:10.3928/00989134-20171206-01.
50. Coombs LA, Hunt L, Cataldo J. A Scoping Review of the Nurse Practitioner Workforce in Oncology. Cancer Medicine, 2016 Aug;5(8):1908-16, PMID: 27264203; doi:10.1002/cam4.769.
51. Coombs L. The Growing Nurse Practitioner Workforce in Specialty Care. Journal for Nurse Practitioners, 2015 Oct;11 (9): 907-909 doi:10.1016/j.nurpra.2015.06.014.
In Press
1. Gigas E, Zou B, Coombs LA, Schmidt P, Wilmoth MC, Khairat S. 2026 COVID-19 in Appalachian State Veterans Homes: Cases, Mortality and Vaccination Outcomes Military Medicine (Accepted for publication, October 5, 2026)
Co-Investigator, A Mixed Methods Study of Diagnostic Delay in Ovarian and Uterine Cancer PI: Thompson $200,000 Ovarian Cancer Research Alliance (OCRA) 3/2025-2/2027
PI Values assessment tailored for women with metastatic breast cancer and their caregivers: Adaptation and Pilot Study of a Values Assessment Tool (VAST) $90,000 Lineberger Tier 2 Development Awards 7/2022 – 8/2026
PI Supplemental funding existing study for women with metastatic breast cancer Pilot Study of a Values Assessment Tool (VAST) $10,000 N/A Junior Faculty Development Award 7/2025- 6/2026
MPI Characterizing Delays in Cancer Diagnosis for Underserved Populations in North Carolina $115,000 AcademyHealth Gordon and Betty Moore Foundation 11/2023 –8/2025
Key Collaborator To Study the Advanced Practice Registered Nurse (APRN) Workforce in North Carolina $232,000 NC Board of Registered Nursing 2/2023 – 6/2024
Additional Expertise & Specialties: