Examining the impact of a filmed dramatized story intervention for HIV prevention in Latinas 

Principal Investigator: Natalia Villegas Rodriguez, PhD, MSN, RN, IBCLC, FAAN
Funded By: National Institute on Drug Abuse
Timeline: 2022–2024

Latinas continue to be affected disproportionally by HIV in the United States and are often not aware of their HIV status. These disparities indicate that HIV prevention among Latinas is urgent. Dr. Villegas is proposing an innovative intervention to advance HIV prevention for Latinas — a filmed dramatized story (telenovela/soap opera) culturally tailored for Latinas in the US and delivered online.

Abstract: Latinas continue to be affected disproportionally by HIV in the United States (US). Often, Latinas are not aware of their HIV status. Also, their perception of low risk for HIV interferes with condom use, HIV testing and lack of awareness, access, and use of Pre-exposure Prophylaxis [PrEP]. About 60% of total HIV cases in NC occur among women of childbearing age, thus vulnerability to HIV is particularly acute among Latinas between ages 18 and 44 years old, an age group with the highest rate of new HIV infections in NC. These disparities indicate that HIV prevention among Latinas is urgent; therefore, we propose an innovative intervention – a filmed dramatized story (telenovela/soap opera) Infección de Amor (Love Infection) – culturally tailored for Latinas in the US and delivered online. Infección de Amor was filmed and developed but has not been tested with our target audience. The proposed study will pilot test IA and move the intervention to online using a website that will allow individual access around the clock from any location and device, such as a smartphone, ensuring wide dissemination of the intervention in the future. We propose a two-year planning grant (R34) to prepare for an R01 efficacy trial. Our aims are to: 1) Develop the intervention delivery website, conduct a website usability test, and test the feasibility and acceptability of the IA intervention (four telenovela episodes) with 10 Latinas, 2) Conduct a randomized controlled pilot study to examine change in HIV prevention behaviors (condom use; HIV testing; and PrEP awareness, access, and use) comparing 71 intervention and 71 control Latinas from baseline (Time 1 [T1], 0 months) to post-active intervention (Time 2 [T2], 1 month), and to six months follow-up, a period with no contact from the study staff (Time 3 [T3, 7 months]), and 3) Complete establishing the study infrastructure, expanding our multidisciplinary team, building our research partnerships with the community, finalize the protocol and training materials, refine recruitment and retention strategies, data collection and data management procedures, and obtain institutional review board approval in preparation for an R01 efficacy study. We address the National Institute on Drug Abuse (NIDA) goal #4: increase NIDA research and programs’ public impact. We aim to use a novel intervention to advance HIV prevention for Latinas. We will implement a culturally durable and feasible intervention for Latinas.